Ziti alla palermitana is a traditional Sicilian pasta dish originating from Palermo. The dish is usually made with a combination of ziti pasta, tuna, tomatoes, onions, garlic, anchovies, oregano, olive oil, salt, pepper, and grated caciocavallo cheese.

The onions, garlic, tomatoes, oregano, and anchovies are sautéed in olive oil, then mixed with the tuna and seasonings. The ziti is boiled in salted water until al dente, drained, then dressed with the sauce and topped with grated caciocavallo before serving.