Mavrud is a highly valued, native Bulgarian grape variety that is predominantly grown in the province of Plovdiv. This late-ripening, dark-skinned grape particularly thrives in warmer climates, and it is used in the production of single varietal wines and blends.

Shiroka Melnishka Loza is an ancient, late-ripening Bulgarian grape variety that is predominantly grown in southwestern parts of the country, in the regions of Melnik, Petrich, and Sandanski. The grape produces age-worthy varietal wines that are rich in tannins and typically display notes and aromas of cherries, strawberries, and stone fruit, while matured varieties develop into more complex nuances of tar, leather, and spices.

Kadarka is a red grape with an uncertain origin. It is most likely a native Balkan variety that spread during Ottoman rule. Due to its finicky nature, it has slightly declined in popularity, but it is still an important red variety, especially in Hungary.

Believed to be native to Bulgaria, this plump white grape is predominantly cultivated in the eastern parts of the country. Varietal Dimiat wines are typically aromatic, light, and fresh and usually display fruity aromas of apricots and quince.

Melnik 55 or Ranna Melnishka Loza is a Bulgarian grape variety created as a cross between Melnik (Shiroka Melnishka Loza) and a mixture of pollen from Valdiguié, Durif, and Jurançon. It was later proven that the other parent was Valdiguié.

Misket Cherven is a native Bulgarian grape used in the production of fragrant white wines—the word red merely refers to the pink hue of the grape. This late-ripening variety is cultivated in several Bulgarian regions, and along with winemaking, it is also enjoyed as a table grape.

Rubin is a Bulgarian grape created in the 1940s at the Institute of Viticulture and Enology in Pleven. The grape is a cross between French Syrah and Italian Nebbiolo. It is a very resilient grape that ripens relatively early. Although it is mainly used in blends, varietal examples are becoming more common.